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1-Chloroethyl chloroformate, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals L1419714
Description
1-Chloroethyl chloroformate acts as a reagent in the selective N-dealkylation of tertiary amines. It is also used as a reactant in the preparation of alkyl 1-chloroethyl carbonates. Further, it is used for N-demethylation reaction in the determination of multiple drugs of abuse in biological fluids using capillary electrophoresis with native fluorescence and laser-induced fluorescence detection. It plays an important role as a catalyst for the chemoselective desilylation of silyl-protected alcohols. In addition to this, it is used to cleave benzhydryl groups from amines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1-Chloroethyl chloroformate acts as a reagent in the selective N-dealkylation of tertiary amines. It is also used as a reactant in the preparation of alkyl 1-chloroethyl carbonates. Further, it is used for N-demethylation reaction in the determination of multiple drugs of abuse in biological fluids using capillary electrophoresis with native fluorescence and laser-induced fluorescence detection. It plays an important role as a catalyst for the chemoselective desilylation of silyl-protected alcohols. In addition to this, it is used to cleave benzhydryl groups from amines.
Solubility
Miscible with most organic solvents.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agent, strong base, alcohols and amines.
Specifications
| 1-Chloroethyl chloroformate | |
| -65°C | |
| 119°C to 121°C | |
| C3H4Cl2O2 | |
| MFCD00000647 | |
| UN2742 | |
| Moisture sensitive | |
| Miscible with most organic solvents. | |
| CC(Cl)OC(Cl)=O | |
| 142.96 | |
| 142.97 |
| 50893-53-3 | |
| 1.312 | |
| 45°C (113°F) | |
| 1.423 | |
| 25 g | |
| 1747601 | |
| 1-chloroethyl chloroformate, chloroformic acid 1-chloroethyl ester, 1-chloro ethyl chloroformate, 1-chloroethylchloroformate, carbonochloridic acid, 1-chloroethyl ester, ace-cl, alpha-chloroethyl chloroformate, chloro 1-chloroethoxy methanone, .alpha.-chloroethyl chloroformate, pubchem17418 | |
| QOPVNWQGBQYBBP-UHFFFAOYNA-N | |
| 1-chloroethyl carbonochloridate | |
| 521305 | |
| 98% |
Chemical Identifiers
| 50893-53-3 | |
| 142.96 | |
| QOPVNWQGBQYBBP-UHFFFAOYNA-N | |
| 521305 | |
| CC(Cl)OC(Cl)=O |
| C3H4Cl2O2 | |
| MFCD00000647 | |
| 1-chloroethyl chloroformate, chloroformic acid 1-chloroethyl ester, 1-chloro ethyl chloroformate, 1-chloroethylchloroformate, carbonochloridic acid, 1-chloroethyl ester, ace-cl, alpha-chloroethyl chloroformate, chloro 1-chloroethoxy methanone, .alpha.-chloroethyl chloroformate, pubchem17418 | |
| 1-chloroethyl carbonochloridate |
Safety and Handling
GHS H Statement
H330-H314-H318-H226-H302
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if swallowed.
P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
H226-H302-H314-H330
DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: CHLOROFORMATES, TOXIC, CORROSIVE, FLAMMABLE, N.O.S.
EINECSNumber : 256-834-2
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only