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2-(Chloromethoxy)ethyltrimethylsilane, tech. 90%, stab. with 0.1% N,N-Diisopropylethylamine, Thermo Scientific Chemicals

$74.05 - $838.47

Chemical Identifiers

CAS 76513-69-4
Molecular Formula C6H15ClOSi
Molecular Weight (g/mol) 166.72
MDL Number MFCD00009919
InChI Key BPXKZEMBEZGUAH-UHFFFAOYSA-N
Synonym 2-trimethylsilyl ethoxymethyl chloride, 2-chloromethoxy ethyl trimethylsilane, sem-chloride, 2-trimethylsilyl ethoxymethylchloride, sem-cl, 2-chloromethyl 2-trimethylsilyl ethyl ether, semcl, 2-chloromethoxy ethyl-trimethylsilane, 2-trimethysilyl-ethoxymethyl chloride
PubChem CID 2724271
IUPAC Name 2-(chloromethoxy)ethyl-trimethylsilane
SMILES C[Si](C)(C)CCOCCl
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Products 3
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AAH5507403
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Thermo Scientific Chemicals
H5507403
1 g
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AAH5507406
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Thermo Scientific Chemicals
H5507406
5 g
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AAH5507414
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Thermo Scientific Chemicals
H5507414
25 g
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Description

Description

2-(Chloromethoxy)ethyltrimethylsilane is used in the preparation of SEM [2-(trimethylsilyl)ethoxy]methyl]-ethers. It serves as a phenol protecting group in the synthesis of laterifluorones. Further, it reacts with 1H-imidazole to prepare 1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-(Chloromethoxy)ethyltrimethylsilane is used in the preparation of SEM [2-(trimethylsilyl)ethoxy]methyl]-ethers. It serves as a phenol protecting group in the synthesis of laterifluorones. Further, it reacts with 1H-imidazole to prepare 1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
Specifications

Chemical Identifiers

76513-69-4
166.72
BPXKZEMBEZGUAH-UHFFFAOYSA-N
2724271
C[Si](C)(C)CCOCCl
C6H15ClOSi
MFCD00009919
2-trimethylsilyl ethoxymethyl chloride, 2-chloromethoxy ethyl trimethylsilane, sem-chloride, 2-trimethylsilyl ethoxymethylchloride, sem-cl, 2-chloromethyl 2-trimethylsilyl ethyl ether, semcl, 2-chloromethoxy ethyl-trimethylsilane, 2-trimethysilyl-ethoxymethyl chloride
2-(chloromethoxy)ethyl-trimethylsilane

Specifications

170°C to 172°C
1 g
(CH3)3SiCH2CH2OCH2Cl
UN2920
46°C (115°F)
BPXKZEMBEZGUAH-UHFFFAOYSA-N
2-(chloromethoxy)ethyl-trimethylsilane
2724271
90%
1.435
0.942
76513-69-4
C6H15ClOSi
MFCD00009919
3587289
2-trimethylsilyl ethoxymethyl chloride, 2-chloromethoxy ethyl trimethylsilane, sem-chloride, 2-trimethylsilyl ethoxymethylchloride, sem-cl, 2-chloromethyl 2-trimethylsilyl ethyl ether, semcl, 2-chloromethoxy ethyl-trimethylsilane, 2-trimethysilyl-ethoxymethyl chloride
C[Si](C)(C)CCOCCl
166.72
166.72
Technical
Moisture sensitive
2-(Chloromethoxy)ethyltrimethylsilane, stabilized with 0.3% N-ethyldiisopropylamine
Safety and Handling

Safety and Handling

GHS H Statement
H314-H318-H226
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.

P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

H226-H314-H335

DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.

EINECSNumber : 278-483-4

TSCA : No

Recommended Storage : Keep cold; Store under Nitrogen

SDS
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RUO – Research Use Only