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Thermo Scientific Chemicals 3,4-Dihydroxy-L-phenylalanine, 98+%
3-(3,4-Dihydroxyphenyl)-L-alanine (levodopa orL-dopa), CAS # 59-92-7, is a dopamine precursor molecule.
Supplier: Thermo Scientific Chemicals A1131106
Description
3,4-dihydroxy-L-phenylalanine (DOPA) is used as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells. It is also used as an anticholinergic drug and used in the treatment of Parkinson's disease. It acts as an intermediate in the biosynthesis of other catecholamines (norepinephrine, epinephrine) and melanin. It acts as a precursor of dopamine product of tyrosine hydroxylase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• 3-(3,4-Dihydroxyphenyl)-L-alanine, or L-dopa, is converted to dopamine by DOPA decarboxylase in the body
• Upon conversion to dopamine, it acts as an excitatory neurotransmitter
Applications
• L-dopa is useful in the laboratory study of Parkinson’s to replenish dopamine in depleted circuits
• L-dopa has also been used for laboratory research on hypertension and melanocyte activity
Specifications
| ∼295°C (decomposition) | |
| 59-92-7 | |
| MFCD00002598 | |
| 14,5464 | |
| Slightly soluble in water,dilute hydrochloric acid and formic acid. Insoluble in ethanol. | |
| N[C@@H](CC1=CC=C(O)C(O)=C1)C(O)=O | |
| 197.19 | |
| 6047 | |
| Odorless | |
| ≥98% |
| 3,4-Dihydroxy-L-phenylalanine | |
| C9H11NO4 | |
| 2215169 | |
| levodopa, l-dopa, dopar, 3-hydroxy-l-tyrosine, 3,4-dihydroxy-l-phenylalanine, larodopa, bendopa, levopa, dihydroxy-l-phenylalanine, cidandopa | |
| WTDRDQBEARUVNC-LURJTMIESA-N | |
| (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid | |
| 5 g | |
| CHEBI:15765 | |
| 197.19 | |
| Light sensitive |
Chemical Identifiers
| 59-92-7 | |
| 197.19 | |
| WTDRDQBEARUVNC-LURJTMIESA-N | |
| 6047 | |
| (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid |
| C9H11NO4 | |
| MFCD00002598 | |
| levodopa, l-dopa, dopar, 3-hydroxy-l-tyrosine, 3,4-dihydroxy-l-phenylalanine, larodopa, bendopa, levopa, dihydroxy-l-phenylalanine, cidandopa | |
| CHEBI:15765 | |
| N[C@@H](CC1=CC=C(O)C(O)=C1)C(O)=O |
Safety and Handling
GHS H Statement
H301
Toxic if swallowed.
P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P362-P501c
H302-H315-H319
EINECSNumber : 200-445-2
RTECSNumber : AY5600000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only