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3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%, Thermo Scientific Chemicals

$282.85 - $814.67

Chemical Identifiers

CAS 92921-24-9
Molecular Formula C16H17N2NaO9S
Molecular Weight (g/mol) 436.367
MDL Number MFCD00054978
InChI Key VUFNRPJNRFOTGK-UHFFFAOYSA-M
Synonym sulfo-smcc, sodium 1-4-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl methyl cyclohexanecarbonyl oxy-2,5-dioxopyrrolidine-3-sulfonate, sulfo-smcc sodium, 4-maleimidomethyl cyclohexane-1-carboxylic acid 3-sulfo-n-hydroxysuccinimide ester sodium salt, 3-sulfo-n-succinimidyl 4-n-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-trans-smcc, sulfo-smcc crosslinker, sulfo-n-succinimidyl 4-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-smcc sodium salt, bicl207
PubChem CID 4618794
IUPAC Name sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
SMILES C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
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Products 2
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AAH54807MB
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Thermo Scientific Chemicals
H54807MB
25 mg
Each for $282.85
 
AAH54807MC
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Thermo Scientific Chemicals
H54807MC
100 mg
Each for $814.67
 
Description

Description

3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Solubility
Soluble in water (2.5 mg/ml) and dimethyl formamide.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
Specifications

Chemical Identifiers

92921-24-9
436.367
VUFNRPJNRFOTGK-UHFFFAOYSA-M
4618794
C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
C16H17N2NaO9S
MFCD00054978
sulfo-smcc, sodium 1-4-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl methyl cyclohexanecarbonyl oxy-2,5-dioxopyrrolidine-3-sulfonate, sulfo-smcc sodium, 4-maleimidomethyl cyclohexane-1-carboxylic acid 3-sulfo-n-hydroxysuccinimide ester sodium salt, 3-sulfo-n-succinimidyl 4-n-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-trans-smcc, sulfo-smcc crosslinker, sulfo-n-succinimidyl 4-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-smcc sodium salt, bicl207
sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate

Specifications

92921-24-9
MFCD00054978
sulfo-smcc, sodium 1-4-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl methyl cyclohexanecarbonyl oxy-2,5-dioxopyrrolidine-3-sulfonate, sulfo-smcc sodium, 4-maleimidomethyl cyclohexane-1-carboxylic acid 3-sulfo-n-hydroxysuccinimide ester sodium salt, 3-sulfo-n-succinimidyl 4-n-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-trans-smcc, sulfo-smcc crosslinker, sulfo-n-succinimidyl 4-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-smcc sodium salt, bicl207
VUFNRPJNRFOTGK-UHFFFAOYSA-M
sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
4618794
≥98%
C16H17N2NaO9S
25 mg
Soluble in water (2.5mg/ml) and dimethyl formamide.
C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
436.367
436.37
3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

TSCA : No

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only