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4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals B2287714
Description
4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Specifications
| 4',7-Dihydroxyisoflavone | |
| 328°C to 332°C (decomposition) | |
| MFCD00016954 | |
| 231523 | |
| daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone | |
| ZQSIJRDFPHDXIC-UHFFFAOYSA-N | |
| 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one | |
| 5281708 | |
| 254.24 |
| 486-66-8 | |
| C15H10O4 | |
| 25 g | |
| 14,2801 | |
| Insoluble in water. Soluble in DMSO (25mg/ml),ethanol (2mg/ml),DMF (10mg/ml),and 1:10 DMSO:PBS (pH 7.2) (0.15mg/ml). | |
| C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O | |
| 254.241 | |
| CHEBI:28197 | |
| 97% |
Chemical Identifiers
| 486-66-8 | |
| 254.241 | |
| ZQSIJRDFPHDXIC-UHFFFAOYSA-N | |
| 5281708 | |
| 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one |
| C15H10O4 | |
| MFCD00016954 | |
| daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone | |
| CHEBI:28197 | |
| C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
H315-H319
EINECSNumber : 207-635-4
RTECSNumber : DJ3100040
TSCA : No
RUO – Research Use Only