missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Please login to your online account to display your discounted pricing
Thermo Scientific Chemicals 4-Epianhydrotetracycline hydrochloride, can be used as a secondary standard
4-Epianhydrotetracycline hydrochloride, CAS # 4465-65-0, is an antibiotic derivative of tetracycline. It is an important standard for monitoring tetracycline stability and toxicity in laboratory studies.
$422.92 - $1339.16
Chemical Identifiers
| CAS | 4465-65-0 |
|---|---|
| Molecular Formula | C22H22N2O7·HCl |
| Molecular Weight (g/mol) | 462.89 |
| MDL Number | MFCD00151455 |
| InChI Key | SPFAOPCHYIJPHJ-MOMXNFOMSA-N |
| Synonym | 4-epianhydrotetracycline hydrochloride, unii-06y7hm8dba, 06y7hm8dba, 4-epi-anhydrotetracycline hydrochloride, 4-epi-ahydrochloride, 4-epianhydrotetracycline hcl, epianhydrotetracycline hydrochloride, 4-epianhydrotetracycline hydrochloride, vetranal tm , analytical standard, 4-epianhydrotetracycline hydrochloride, european pharmacopoeia ep reference standard, 4-epianhydrotetracycline hydrochloride, united states pharmacopeia usp reference standard |
| PubChem CID | 54682545 |
| IUPAC Name | (4R,4aS,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride |
| SMILES | CC1=C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C.Cl |
| Catalog Number | Mfr. No. | Quantity | Packaging | Price | Quantity | ||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Packaging | Price | Quantity | ||||
|
AC233111000
|
Thermo Scientific Chemicals
233111000 |
100 mg | Glass bottle |
Each for $422.92
|
|
||||
|
AC233115000
|
Thermo Scientific Chemicals
233115000 |
500 mg | Glass bottle |
Each for $1,339.16
|
|
||||
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
- 4-Epianhydrotetracycline hydrochloride is a secondary degradation product formed by epimerization of tetracycline and dehydration at the C6 position to aromatize the B ring
- It has 250-fold higher toxicity than either tetracycline or doxycycline depending on the system under study
Applications
- 4-Epianhydrotetracycline hydrochloride is less toxic to E. coli, and thus suitable for use with vectors or systems designed upon elements of the (Tn10) tet operon of E. coli
- This compound is also used in veterinary medicine research and as a secondary standard for application in quality control in pharmaceutical laboratories
Chemical Identifiers
| 4465-65-0 | |
| 462.89 | |
| SPFAOPCHYIJPHJ-MOMXNFOMSA-N | |
| 54682545 | |
| CC1=C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C.Cl |
| C22H22N2O7·HCl | |
| MFCD00151455 | |
| 4-epianhydrotetracycline hydrochloride, unii-06y7hm8dba, 06y7hm8dba, 4-epi-anhydrotetracycline hydrochloride, 4-epi-ahydrochloride, 4-epianhydrotetracycline hcl, epianhydrotetracycline hydrochloride, 4-epianhydrotetracycline hydrochloride, vetranal tm , analytical standard, 4-epianhydrotetracycline hydrochloride, european pharmacopoeia ep reference standard, 4-epianhydrotetracycline hydrochloride, united states pharmacopeia usp reference standard | |
| (4R,4aS,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride |
Specifications
| 4465-65-0 | |
| 100.0 | |
| Orange | |
| 80% min. (as is,calculated) | |
| C22H22N2O7·HCl | |
| 100 mg | |
| 4-epianhydrotetracycline hydrochloride, unii-06y7hm8dba, 06y7hm8dba, 4-epi-anhydrotetracycline hydrochloride, 4-epi-ahydrochloride, 4-epianhydrotetracycline hcl, epianhydrotetracycline hydrochloride, 4-epianhydrotetracycline hydrochloride, vetranal tm , analytical standard, 4-epianhydrotetracycline hydrochloride, european pharmacopoeia ep reference standard, 4-epianhydrotetracycline hydrochloride, united states pharmacopeia usp reference standard | |
| SPFAOPCHYIJPHJ-MOMXNFOMSA-N | |
| (4R,4aS,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride | |
| 54682545 | |
| ≥97.0% Total Base (on anhydrous substance), ≥80 wt% (as is, calculated) (HPLC) | |
| 4-Epianhydrotetracycline hydrochloride, 97% |
| 96.0 | |
| 220.0°C | |
| Authentic | |
| Glass bottle | |
| MFCD00151455 | |
| − 279.00 | |
| Solubility in water: 0.9g/L. Other solubilities: 25g/L methanol | |
| CC1=C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C.Cl | |
| 462.89 | |
| 462.89 | |
| Powder |
Safety and Handling
GHS H Statement:
Causes serious eye irritation.
Harmful if swallowed.
Suspected of damaging the unborn child.
GHS P Statement:
Use personal protective equipment as required.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
GHS Signal Word: Warning
RUO – Research Use Only