TYROBP Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier: Thermo Fisher Scientific PA112701

Catalog No. 01-674-839

$719.50 / Each

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Description

A suggested positive control for this product is NKp44 positive cells.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Specifications

Antigen	TYROBP
Classification	Polyclonal
Conjugate	Unconjugated
Gene	TYROBP
Gene Alias	DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp
Host Species	Rabbit
Purification Method	Ammonium sulfate precipitation
Regulatory Status	RUO
Gene ID (Entrez)	22177, 7305
Content And Storage	-20° C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	Immunoprecipitation, Western Blot
Concentration	1 mg/mL
Formulation	PBS with 0.08% sodium azide
Gene Accession No.	O43914, O54885
Gene Symbols	TYROBP
Immunogen	Recombinant DAP12 protein.
Quantity	100 μg
Primary or Secondary	Primary
Target Species	Human, Mouse
Product Type	Antibody
Isotype	IgG

TYROBP Polyclonal Antibody, Invitrogen™

Description

Specifications

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