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toll-like receptor 8, Mouse, Clone: 4C6, Abnova™
Mouse monoclonal antibody raised against a partial recombinant TLR8.
Supplier: Abnova Corporation H00051311M01
Description
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq
Sequence: RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDSpécifications
| toll-like receptor 8 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_138636 | |
| TLR8 | |
| TLR8 (NP_619542, 723 a.a. ∼ 825 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Membrane Receptors | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Western Blot | |
| 4C6 | |
| Mouse monoclonal antibody raised against a partial recombinant TLR8. | |
| TLR8 | |
| CD288/MGC119599/MGC119600 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Yes | |
| 51311 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2b κ |