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Astemizole, 99+%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals J60339MF
Description
Astemizole, is used as a potent and selective H1-receptor antagonist that displays antihistamine and antimalarial activity. It is also been used as a chaperone to correct folding defects and restore protein function for some mutated forms of hERG channels.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilityIt is soluble in DMSO (25 mg/ml ), ethanol (25 mg/ml), chloroform, methanol, and water (partly miscible).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storag
Specifications
| Astemizole | |
| 149°C to 150°C | |
| C28H31FN4O | |
| 50 mg | |
| astemizole, hismanal, histaminos, paralergin, laridal, retolen, alermizol, astemison, astemizol, histamen | |
| GXDALQBWZGODGZ-UHFFFAOYSA-N | |
| 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine | |
| 2247 | |
| 458.57 | |
| Powder |
| 68844-77-9 | |
| White | |
| MFCD00153919 | |
| 14,856 | |
| It is soluble in DMSO (25mg/ml ),ethanol (25mg/ml),chloroform,methanol,and water (partly miscible). | |
| COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F | |
| 458.581 | |
| CHEBI:2896 | |
| ≥99% |
Chemical Identifiers
| 68844-77-9 | |
| 458.581 | |
| GXDALQBWZGODGZ-UHFFFAOYSA-N | |
| 2247 | |
| 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine |
| C28H31FN4O | |
| MFCD00153919 | |
| astemizole, hismanal, histaminos, paralergin, laridal, retolen, alermizol, astemison, astemizol, histamen | |
| CHEBI:2896 | |
| COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 272-441-9
RTECSNumber : DD8968000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only