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Beclin 1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Fisher Scientific PA118287
Description
PA1-18287 detects Beclin-1 from human samples. PA1-18287 has been successfully used in immunohistochemistry and immunofluorescence procedures. The PA1-18287 immunogen is a synthetic peptide corresponding to the C-terminal residues of human Beclin-1, conjugated to Blue Carrier Protein. The sequence is 100% conserved in mouse and rat. Reconstitute with 100 μL of distilled water.
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.Specifications
| Beclin 1 | |
| Polyclonal | |
| Unconjugated | |
| BECN1 | |
| 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097 | |
| Rabbit | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunohistochemistry (Frozen) | |
| Conc. Not Determined | |
| whole serum with no preservative | |
| Q14457 | |
| BECN1 | |
| Synthetic peptide corresponding to the C-terminal residues of human Beclin-1. | |
| RUO | |
| 8678 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |