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Benzyloxyacetyl chloride, 95%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals L1433706
Description
Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsBenzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.
Solubility
Reacts with water.
Notes
It is sensitive to moisture. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature is 2 - 8°C. Store under inert gas.
Specifications
Benzyloxyacetyl chloride | |
1.189 | |
>110°C (230°F) | |
1.523 | |
MFCD00010768 | |
UN3265 | |
Moisture sensitive | |
Reacts with water. | |
C1=CC=C(C=C1)COCC(=O)Cl | |
184.619 | |
184.62 |
19810-31-2 | |
84°C to 87°C (0.4 mmHg) | |
C9H9ClO2 | |
C6H5CH2OCH2COCl | |
5 g | |
1947363 | |
benzyloxyacetyl chloride, 2-benzyloxy acetyl chloride, benzyloxy acetyl chloride, benzyloxyacetylchloride, benzyloxy-acetyl chloride, benzyloxyacetic acid chloride, acetyl chloride, phenylmethoxy, acetyl chloride, benzyloxy, alpha-benzyloxy acetyl chloride, bnoch2cocl | |
QISAUDWTBBNJIR-UHFFFAOYSA-N | |
2-phenylmethoxyacetyl chloride | |
177085 | |
95% |
Chemical Identifiers
19810-31-2 | |
184.619 | |
QISAUDWTBBNJIR-UHFFFAOYSA-N | |
177085 | |
C1=CC=C(C=C1)COCC(=O)Cl |
C9H9ClO2 | |
MFCD00010768 | |
benzyloxyacetyl chloride, 2-benzyloxy acetyl chloride, benzyloxy acetyl chloride, benzyloxyacetylchloride, benzyloxy-acetyl chloride, benzyloxyacetic acid chloride, acetyl chloride, phenylmethoxy, acetyl chloride, benzyloxy, alpha-benzyloxy acetyl chloride, bnoch2cocl | |
2-phenylmethoxyacetyl chloride |
Safety and Handling
GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
H314-H335
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only