missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Castanospermine, 99%, Thermo Scientific Chemicals

Potent alpha and beta-glucosidase inhibitor

Supplier:  Thermo Scientific Chemicals J61071MC

 View more versions of this product

Catalog No. AAJ61071MC


Explore available promotions

Description

Description

Castanospermine, is used as a glycosidase inhibitor and antiinflammatory agent.castanospermine is used to inhibit syncytium formation between HIV-infected and CD4-expressing cells and may also interfere with infectivity. It has also been demonstrated that this agent inhibits inflammation at the level of leukocyte extravasation in rat models of experimental adjuvant-induced arthritis and autoimmune encephalomyelitis. Castanospermine is an inhibitor of Glucosidase I, Maltase-glucoamylase, and MANBA. Potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Castanospermine, is used as a glycosidase inhibitor and antiinflammatory agent.castanospermine is used to inhibit syncytium formation between HIV-infected and CD4-expressing cells and may also interfere with infectivity. It has also been demonstrated that this agent inhibits inflammation at the level of leukocyte extravasation in rat models of experimental adjuvant-induced arthritis and autoimmune encephalomyelitis. Castanospermine is an inhibitor of Glucosidase I, Maltase-glucoamylase, and MANBA. Potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

Solubility
Soluble in water

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
Specifications

Specifications

Castanospermine
213°C to 217°C
C8H15NO4
100 mg
14,1896
Soluble in water
C1CN2CC(C(C(C2C1O)O)O)O
189.211
CHEBI:27860
99%
79831-76-8
White
MFCD00017555
3588654
castanospermine, castinospermine, 1,6,7,8-tetrahydroxyoctahydroindolizine, 1s,6s,7r,8r,8ar-1,6,7,8-tetrahydroxyindolizidine, 6-epicastanospermine, unii-q0i3184xm7, 6,7-diepicastanospermine, castanospermine, castanospermum australe, 1s,6s,7r,8ar-tetrahydroxyoctahydroindolizine, 1s,6s,7r,8r,8ar-octahydroindolizine-1,6,7,8-tetrol
JDVVGAQPNNXQDW-TVNFTVLESA-N
(1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,7,8-tetrol
54445
189.21
Solid

Chemical Identifiers

79831-76-8
189.211
JDVVGAQPNNXQDW-TVNFTVLESA-N
54445
(1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,7,8-tetrol
C8H15NO4
MFCD00017555
castanospermine, castinospermine, 1,6,7,8-tetrahydroxyoctahydroindolizine, 1s,6s,7r,8r,8ar-1,6,7,8-tetrahydroxyindolizidine, 6-epicastanospermine, unii-q0i3184xm7, 6,7-diepicastanospermine, castanospermine, castanospermum australe, 1s,6s,7r,8ar-tetrahydroxyoctahydroindolizine, 1s,6s,7r,8r,8ar-octahydroindolizine-1,6,7,8-tetrol
CHEBI:27860
C1CN2CC(C(C(C2C1O)O)O)O
Videos
Safety and Handling

Safety and Handling

GHS H Statement
H302-H312-H332
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c

H302+H312+H332

TSCA : No

Recommended Storage : Keep cold

SDS
Documents

Documents

Promotions

Promotions

RUO – Research Use Only