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Cerulenin, 98%, Thermo Scientific Chemicals

Has antibiotic and antifungal properties; inhibits fatty acid and steroid biosynthesis

Supplier:  Thermo Scientific Chemicals J64538MA

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Catalog No. AAJ64538MA


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Description

Description

Cerulenin is used as an antifungal antibiotic that inhibits sterol and fatty acids biosynthesis. Cerulenin induces apoptosis in tumor cell lines. It can be a useful biochemical tool with applications for the study of metabolism and function of fatty acids in the bacterial cell membrane and in yeast. An extensive review including the properties, uses, mechanism of action and structure has been reported.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cerulenin is used as an antifungal antibiotic that inhibits sterol and fatty acids biosynthesis. Cerulenin induces apoptosis in tumor cell lines. It can be a useful biochemical tool with applications for the study of metabolism and function of fatty acids in the bacterial cell membrane and in yeast. An extensive review including the properties, uses, mechanism of action and structure has been reported.

Solubility
Soluble in acetone at 20mg/ml. Also soluble in ethanol, benzene, chloroform, or ethyl acetate.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers..
Specifications

Specifications

Cerulenin
Powder
White to Yellow
C12H17NO3
4140423
(2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide
GVEZIHKRYBHEFX-NQQPLRFYSA-N
(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
5282054
223.27
Cerulenin
17397-89-6
10 mg
MFCD00077686
14,2004
Soluble in acetone at 20mg/ml; Also soluble in ethanol,benzene,chloroform,or ethyl acetate.
CC=CCC=CCCC(=O)C1C(O1)C(=O)N
223.272
CHEBI:171741
98%

Chemical Identifiers

17397-89-6
223.272
GVEZIHKRYBHEFX-NQQPLRFYSA-N
5282054
(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
C12H17NO3
MFCD00077686
(2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide
CHEBI:171741
CC=CCC=CCCC(=O)C1C(O1)C(=O)N
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Safety and Handling

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

P264b-P270-P301+P312-P330-P501c

H302

EINECSNumber : 241-424-8

RTECSNumber : JR1670000

TSCA : No

Recommended Storage : Store at -20°C

SDS
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RUO – Research Use Only