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Dobutamine hydrochloride, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals J61333MD
Description
Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1M.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsDobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.
Solubility
Soluble in water or ethanol with warming. Also soluble in methanol
Notes
Solutions oxidize readily at pH greater than 11. Protect solutions from light
Specifications
| Dobutamine hydrochloride | |
| 184°C to 186°C | |
| C18H24ClNO3 | |
| 250 mg | |
| dobutamine hydrochloride, dobutamine hcl, dobutrex, inotrex, dl-dobutamine hydrochloride, dobutamina clorhidrato spanish, 4-2-4-4-hydroxyphenyl butan-2-ylamino ethyl benzene-1,2-diol hydrochloride, +--4-2-3-p-hydroxyphenyl-1-methylpropyl amino ethyl pyrocatechol hydrochloride, 1,2-benzenediol, 4-2-3-4-hydroxyphenyl-1-methylpropyl amino ethyl-, hydrochloride, +- | |
| BQKADKWNRWCIJL-UHFFFAOYNA-N | |
| hydrogen 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol chloride | |
| 65324 | |
| 337.85 |
| 49745-95-1 | |
| White | |
| MFCD00153795 | |
| 14,3395 | |
| Soluble in water or ethanol with warming; Also soluble in methanol | |
| [H+].[Cl-].CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1 | |
| 337.84 | |
| CHEBI:4671 | |
| Powder |
Chemical Identifiers
| 49745-95-1 | |
| 337.84 | |
| BQKADKWNRWCIJL-UHFFFAOYNA-N | |
| 65324 | |
| hydrogen 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol chloride |
| C18H24ClNO3 | |
| MFCD00153795 | |
| dobutamine hydrochloride, dobutamine hcl, dobutrex, inotrex, dl-dobutamine hydrochloride, dobutamina clorhidrato spanish, 4-2-4-4-hydroxyphenyl butan-2-ylamino ethyl benzene-1,2-diol hydrochloride, +--4-2-3-p-hydroxyphenyl-1-methylpropyl amino ethyl pyrocatechol hydrochloride, 1,2-benzenediol, 4-2-3-4-hydroxyphenyl-1-methylpropyl amino ethyl-, hydrochloride, +- | |
| CHEBI:4671 | |
| [H+].[Cl-].CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1 |
Safety and Handling
GHS H Statement
H361-H302-H312-H332
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
P201-P202-P261-P264b-P270-P271-P281-P301+P312-P302+P352-P304+P340-P308+P313-P312-P330-P363-P501c
H302+H312+H332-H361
EINECSNumber : 256-464-1
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only