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EIF2S1 Monoclonal Antibody (EIF2-alpha), Invitrogen™ DFS Item

Mouse Monoclonal Antibody

Supplier:  Invitrogen AHO0802

Catalog No. AHO0802


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Description

Description

This antibody recognizes the alpha subunit of eukaryotic translation initiation factor 2 (EIF2-alpha). Recommended positive control are human Jurkat, CEM, and HeLa cells; mouse 3T3L1 cells; and rat PC-12 cells.

EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
Specifications

Specifications

EIF2S1
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide; pH 7.4
P05198, P68101, Q6ZWX6
EIF2S1
Recombinant human eIF-2-alpha.
100 μg
Primary
Human, Mouse, Non-human Primate, Rat
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunoprecipitation, Western Blot
EIF2-alpha
Unconjugated
EIF2S1
0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01
Mouse
Protein A/G
RUO
13665, 1965, 54318
-20°C
Liquid
SDS
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