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Cytiva MabSelect Sure™ Chromatography Media
MabSelect™ SuRe™ is a protein A affinity medium for capturing MAbs at process scale with an alkali-tolerant rProtein A ligand that allows the for cost-effective sanitization protocols
Supplier: Cytiva 17543802
Description
Has an alkali-tolerant rProteain A ligand designed to enhance protease resistance to produce monoclonal antibodies
- Withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH
- Design gives enhanced protease resistance resulting in lower ligand leakage
- Generic elution profile for different monoclonal antibodies enables platform approach to purification
- High-flow agarose matrix allows the processing of large feed volumes
- Used in the commercial manufacture of monoclonal antibodies
Specifications
| 200 mL | |
| Stable in aqueous Buffers commonly used in Protein A Chromatography | |
| 30 mg Human lgG/mL (at 2.4 min. residence time) | |
| <500 cm/Hoμr | |
| 7.87 in. | |
| Certificate of Analysis | |
| Highly Cross-Linked Agarose | |
| 20% Ethanol |
| For Use of Rigorous and Cost-Effective CIP and Sanitization Protocols, Manufacture of Monoclonal Antibodies | |
| 2°C to 8°C | |
| MabSelect SuRe Media | |
| 85 μm | |
| 20 cm | |
| <200 kPa | |
| 3 to 12 | |
| Alkali-stabilized Protein A-derived (E. coli) |