Genlantis™ PrimaPure™ Human Aortic Endothelial Cells (HAOEC) and Kits 

Description

Human Aortic Endothelial Cells (HAOEC) are primary endothelial cells isolated from normal human aorta. They are cryopreserved at second passage and can be cultured and propagated at least 16 population doublings. They respond to cytokine stimulation by expressing cell adhesion molecules. Aortic endothelial cells have been used as an in vitro model for the study of morphological and ultra-structural changes¹ in the development of atherosclerosis. HAOEC system has also been used for the study of endothelial cell-dependent lymphocyte activation² and chemoattractant activity for lymphocytes³ in relation to the degree of atherosclerosis.

• Each lot functionally characterized
• Single donors to allow variability comparisons
• Each lot tested negative for HIV, Hepatitis B & C, mycoplasma, bacteria, yeast, and fungi
• Performance guaranteed with Genlantis media and reagents

REFERENCES:
1. Antonor, A.S. et al, Atherosclerosis 59:1 (1986).
2. Ashida, E.R. et al, J. Clin. Invest. 67:1490 (1981).
3. Farber, H.W. et al, Amer. J. Physiol. 262 (4 parts): H1088 (1992).

†Each kit contains an ampule of cryopreserved HAOEC (PH30405A), 500mL of Endothelial Cell Growth Medium (PM211500), and a Subculture Reagent Kit (PR090100K).