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Invitrogen™ H2A.Zac pan-acetyl (K4,K7,K11,K13) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5114690
Description
Antibody detects endogenous levels of Acetyl-H2A.Z only when acetylated at Lys4/7/11/13.
H2A.Zac pan-acetyl (K4,K7,K11,K13) is classified under histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.Specifications
| H2A.Zac pan-acetyl (K4,K7,K11,K13) | |
| Polyclonal | |
| Unconjugated | |
| H2AFZ | |
| H2A histone family member Z; H2A histone family, member Z; H2A.z; H2a.z-1; H2A/z; H2AFZ; H2az; H2AZ histone; histone H2A.Z | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 3015 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide | |
| P0C0S5 | |
| H2AFZ | |
| A synthesized peptide derived from human H2AFZ(Accession P0C0S5), corresponding to amino acid residues M1-S21. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |