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Thermo Scientific Chemicals Hydrocortisone, 98%
Hydrocortisone, CAS # 50-23-7, is the pharmaceutical formulation of the hormone, cortisol, and is commonly administered as an immunosuppressive drug.
Supplier: Thermo Scientific Chemicals 352450010
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Hydrocortisone is the synthetic formulation of the naturally occurring hormone, cortisol
• It is available as a white crystalline powder soluble in water, DMSO, and ethanol
• It is stable at room temperature but sensitive to light, and reactive in the presence of strong oxidizing agents
Applications
• Hydrocortisone works as an agonist to glucocorticoid receptors, thereby suppressing the inflammatory response of the immune system
• It’s administration induces gluconeogenesis, thus increasing endogenous blood sugar levels
• Research indicates a role for hydrocortisone in the metabolism of fat, protein, and carbohydrates
Specifications
| Hydrocortisone | |
| 212°C to 217°C | |
| Authentic | |
| Glass bottle | |
| MFCD00011654 | |
| 15, 4824 | |
| + 150 | |
| Solubility in water: 0.28g/L (25°C). Other solubilities: soluble in sulfuric acid,partially soluble in alcohol and propylene glycol,soluble in dioxane; sol (g/l) (25°C): chcl3 1.6;,ether 0.35; etoh 15; meoh 6.2; acetone 9.3;,propylene glycol 1 | |
| CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O | |
| 362.47 | |
| CHEBI:17650 | |
| 98% |
| 50-23-7 | |
| White | |
| 97.5% min. (HPLC) | |
| C21H30O5 | |
| 1 g | |
| +150° (156°C c=1,dioxane) | |
| hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril | |
| JYGXADMDTFJGBT-VWUMJDOOSA-N | |
| (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one | |
| 5754 | |
| 362.47 | |
| Powder |
Chemical Identifiers
| 50-23-7 | |
| 362.47 | |
| JYGXADMDTFJGBT-VWUMJDOOSA-N | |
| 5754 | |
| (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
| C21H30O5 | |
| MFCD00011654 | |
| hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril | |
| CHEBI:17650 | |
| CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O |
Safety and Handling
GHS H Statement
May damage the unborn child.
Suspected of damaging fertility.
GHS P Statement
Obtain special instructions before use.
GHS Signal Word: Danger
EINECSNumber : 200-020-1
RUO – Research Use Only