missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Please login to your online account to display your discounted pricing
Hygromycin B, Thermo Scientific Chemicals
Hygromycin B, CAS # 31282-04-9, is an aminoglycoside compound showing antibiotic activity that kills bacteria through the inhibition of protein synthesis. It also presents anthelmintic activity.
$164.22 - $310.25
Chemical Identifiers
| CAS | 31282-04-9 |
|---|---|
| Molecular Formula | C20H37N3O13 |
| Molecular Weight (g/mol) | 527.524 |
| MDL Number | MFCD06795479 |
| InChI Key | GRRNUXAQVGOGFE-BBMONYMYSA-N |
| PubChem CID | 134129613 |
| IUPAC Name | (3'S,3aS,4S,4'S,5'R,6R,6'R,7R,7aS)-4-[(1R,2S,3R,5S,6S)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol |
| SMILES | CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|
AAJ60681MC
|
Thermo Scientific Chemicals
J60681MC |
100 mg |
Each for $164.22
|
|
|||||
|
AAJ60681MD
|
Thermo Scientific Chemicals
J60681MD |
250 mg |
Each for $252.21
|
|
|||||
|
AAJ6068103
|
Thermo Scientific Chemicals
J6068103 |
1 g |
Each for $310.25
|
|
|||||
Description
An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Hygromycin is an aminoglycosidic compound that shows antibiotic activity. It is produced by Streptomyces hygroscopicus
- Hygromycin acts against both prokaryotic and eukaryotic cells, having the ability to inhibit protein synthesis. It also stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. This compound prevents ribosome translocation during translation elongation by binding the 30S rRNA proximal to the ribosomal E, P, and A sites
Application
- In clinical and plant research, this compound can be used as a marker to select and maintain prokaryotic and eukaryotic cells containing the hygromycin resistance gene
- Hygromycin also presents an anthelmintic activity against nematode parasites of chickens
Chemical Identifiers
| 31282-04-9 | |
| 527.524 | |
| GRRNUXAQVGOGFE-BBMONYMYSA-N | |
| (3'S,3aS,4S,4'S,5'R,6R,6'R,7R,7aS)-4-[(1R,2S,3R,5S,6S)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol |
| C20H37N3O13 | |
| MFCD06795479 | |
| 134129613 | |
| CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N |
Specifications
| Hygromycin B | |
| 31282-04-9 | |
| MFCD06795479 | |
| 14,4852 | |
| GRRNUXAQVGOGFE-BBMONYMYSA-N | |
| (3'S,3aS,4S,4'S,5'R,6R,6'R,7R,7aS)-4-[(1R,2S,3R,5S,6S)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol | |
| 134129613 | |
| Brown | |
| Hygromycin B |
| Lyophilized Powder | |
| C20H37N3O13 | |
| UN3462 | |
| Miscible with water,methanol,buffer solution and ethanol; Immiscible with less polar solvents. | |
| CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N | |
| 527.524 | |
| 527.53 | |
| 100 mg |
Safety and Handling
GHS H Statement
H300-H310-H330-H334-H318-H317
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Causes serious eye damage.
May cause an allergic skin reaction.
P260-P262-P264b-P270-P271-P272-P280-P284-P285-P301+P310-P302+P350-P304+P340-P305+P351+P338-P310-P330-P333+P313-P361-P363-P501c
H300+H310+H330-H317-H318-H334
DOTInformation : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
EINECSNumber : 250-545-5
RTECSNumber : WK2130000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only