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Indole-5-carboxylic acid, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A1862714
Description
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIndole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
Solubility
Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Specifications
Indole-5-carboxylic acid | |
208°C to 212°C | |
MFCD00005678 | |
124391 | |
Soluble in ethanol (50mg/ml),dimethyl sulfoxide and methanol. | |
[O-]C(=O)C1=CC=C2NC=CC2=C1 | |
160.15 | |
161.16 |
1670-81-1 | |
C9H6NO2 | |
25 g | |
indole-5-carboxylic acid, 5-carboxyindole, 5-indolecarboxylic acid, indole-5-carboxylic aicd, pubchem1694, 5-carboxy-1h-indole, indole-5-carboxylicacid, indol-5-carboxylic acid, 5-indole carboxylic acid, indole 5-carboxylic acid | |
IENZCGNHSIMFJE-UHFFFAOYSA-M | |
1H-indole-5-carboxylic acid | |
74280 | |
98% |
Chemical Identifiers
1670-81-1 | |
160.15 | |
IENZCGNHSIMFJE-UHFFFAOYSA-M | |
74280 | |
[O-]C(=O)C1=CC=C2NC=CC2=C1 |
C9H6NO2 | |
MFCD00005678 | |
indole-5-carboxylic acid, 5-carboxyindole, 5-indolecarboxylic acid, indole-5-carboxylic aicd, pubchem1694, 5-carboxy-1h-indole, indole-5-carboxylicacid, indol-5-carboxylic acid, 5-indole carboxylic acid, indole 5-carboxylic acid | |
1H-indole-5-carboxylic acid |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302+H312-H315-H319-H335
EINECSNumber : 216-799-6
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only