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Indole-5-carboxylic acid, 98%, Thermo Scientific Chemicals

Supplier:  Thermo Scientific Chemicals A1862714

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Catalog No. AAA1862714

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Description

Description

Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.

Solubility
Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Specifications

Specifications

Indole-5-carboxylic acid
208°C to 212°C
MFCD00005678
124391
Soluble in ethanol (50mg/ml),dimethyl sulfoxide and methanol.
[O-]C(=O)C1=CC=C2NC=CC2=C1
160.15
161.16
1670-81-1
C9H6NO2
25 g
indole-5-carboxylic acid, 5-carboxyindole, 5-indolecarboxylic acid, indole-5-carboxylic aicd, pubchem1694, 5-carboxy-1h-indole, indole-5-carboxylicacid, indol-5-carboxylic acid, 5-indole carboxylic acid, indole 5-carboxylic acid
IENZCGNHSIMFJE-UHFFFAOYSA-M
1H-indole-5-carboxylic acid
74280
98%

Chemical Identifiers

1670-81-1
160.15
IENZCGNHSIMFJE-UHFFFAOYSA-M
74280
[O-]C(=O)C1=CC=C2NC=CC2=C1
C9H6NO2
MFCD00005678
indole-5-carboxylic acid, 5-carboxyindole, 5-indolecarboxylic acid, indole-5-carboxylic aicd, pubchem1694, 5-carboxy-1h-indole, indole-5-carboxylicacid, indol-5-carboxylic acid, 5-indole carboxylic acid, indole 5-carboxylic acid
1H-indole-5-carboxylic acid
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302+H312-H315-H319-H335

EINECSNumber : 216-799-6

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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