Corning™ Iron-fortified Bovine Calf Serum

Description

Bovine calf serum is often used with robust cell lines when large quantities of serum are needed, such as in the manufacturing of biological drugs and vaccines. Bovine calf serum is derived from calves that are generally less than 22 weeks old. Iron is essential for cellular respiration and metabolism, and for some cell lines, makes up for the lower levels of growth factors and other metabolites found in calf serum when compared to FBS.

This product has been granted a Certificate of Suitability (R0-CEP 2018-305) by the European Directorate for the Quality of Medicines (EDQM), certifying that the product meets the criteria described in the current version of monograph No. 1483 of the European Pharmacopoeia ''Product with risk of transmitting agent of animal spongiform encephalopathies.''

• Using industry leading techniques, blood is aseptically collected at abattoirs, centrifuged to isolate the serum and immediately frozen for testing and further processing
• Raw sera is true pooled and triple 0.1 micron sterile filtered with a Sterility Assurance Level (SAL) of 10^-3
• Every lot must pass USP <71> and EP 2.6.1 sterility testing, growth promotion testing, and test negative for mycoplasma and number of industry-monitored viruses
• Additional testing includes endotoxin, hemoglobin, pH, osmolality, total protein, and a biochemical profile which contains various metals, proteins, hormones, and other metabolites