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Itraconazole, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals J6639014
Description
Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It?s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsItraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It′s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..
Solubility
Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications
| Itraconazole | |
| Powder | |
| 166°C | |
| 25 g | |
| C35H38Cl2N8O4 | |
| 14,5245 | |
| Insoluble in water; Solube in chloroform at 50mg/ml; Slightly soluble in ethanol or methanol | |
| CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1 | |
| 705.64 | |
| 705.63 |
| Itraconazole | |
| 84625-61-6 | |
| White | |
| >110°C (230°F) | |
| MFCD00870168,MFCD00941396 | |
| Oriconazole; R51211 | |
| VHVPQPYKVGDNFY-ZPGVKDDISA-N | |
| 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one | |
| 45039617 | |
| 98% |
Chemical Identifiers
| 84625-61-6 | |
| 705.64 | |
| VHVPQPYKVGDNFY-ZPGVKDDISA-N | |
| 45039617 | |
| CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1 |
| C35H38Cl2N8O4 | |
| MFCD00870168,MFCD00941396 | |
| Oriconazole; R51211 | |
| 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
RTECSNumber : XZ5481000
TSCA : No
storageNote1 : 2° to 8°C
Recommended Storage : Keep cold
RUO – Research Use Only