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Kaempferol, 98+%, Thermo Scientific Chemicals

Supplier:  Thermo Scientific Chemicals J60373MF

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Catalog No. AAJ60373MF


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Description

Description

Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

Solubility
Soluble in DMSO or ethanol to 100mM

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep away fom strong oxidizing agents.
Specifications

Specifications

Kaempferol
276°C to 278°C
C15H10O6
50 mg
14,5274
Soluble in DMSO or ethanol to 100mM
OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1
286.24
CHEBI:28499
≥98%
520-18-3
Yellow
MFCD00016938
304401
kaempferol, kaempherol, kempferol, populnetin, rhamnolutein, robigenin, trifolitin, pelargidenolon, rhamnolutin, swartziol
IYRMWMYZSQPJKC-UHFFFAOYSA-N
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
5280863
286.24
Powder

Chemical Identifiers

520-18-3
286.24
IYRMWMYZSQPJKC-UHFFFAOYSA-N
5280863
OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1
C15H10O6
MFCD00016938
kaempferol, kaempherol, kempferol, populnetin, rhamnolutein, robigenin, trifolitin, pelargidenolon, rhamnolutin, swartziol
CHEBI:28499
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

EINECSNumber : 208-287-6

RTECSNumber : LK9275200

TSCA : No

Recommended Storage : Store at -20°C

SDS
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