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Thermo Scientific™ MethElute™ Reagent (TMPAH)

For accurate, sensitive on-column methylation use Thermo Scientific™ MethElute™ Reagent (TMPAH).

Supplier:  Thermo Scientific™ TS49300

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Catalog No. PI49300


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Description

Description

For accurate, sensitive, on-column methylation and detection by GC analysis use Thermo Scientific™ MethElute™ Reagent (TMPAH). It is ideally suited for the quantitative methylation and detection of barbiturates, sedatives, xanthine bases, phenolic alkaloids, and phenytoin, giving a single quantitative peak for each substance. When the reagent is heated with drug-containing extracts, serum, or urine the drugs containing reactive amino, hydroxyl, and carboxyl functions will be methylated at the reactive sites.

Performance Characteristics

Accuracy comparable or better than the UV/TLC method (GC is superior to UV/TLC when phenobarbitol and phenytoin present)

High precision, with coefficient of variation of 5% or less

High sensitivity; barbiturates deteced down to 0.2 mg/dL

Specifications

Specifications

Room Temperature
Flammable, Toxic
0.2 M
10 mL
GC
Trimethylanilinium hydroxide in Methanol
10 mL
SDS
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For Research Use Only. Not for use in diagnostic procedures.