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Methicillin sodium salt, 90+%, Thermo Scientific Chemicals

 

Supplier:  Thermo Scientific Chemicals J6641403

Catalog No. AAJ6641403


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Description

Description

Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP's are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Methicillin Sodium Salt is inactivated by gastric acid so it is given to cells by other means in which gastric acid is not present in vitro.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP′s are enzymes which catalyze a pentagl
Specifications

Specifications

Methicillin Sodium Salt
Powder
196°C to 197°C (decomposition)
1 g
Light sensitive
MFCD07787409
14,5969
Slightly soluble in acetone; Soluble in ethanol or water
[Na+].COC1=CC=CC(OC)=C1C(=O)N[C@H]1[C@H]2SC(C)(C)[C@@H](N2C1=O)C([O-])=O
402.40
CHEBI:52065
98%
Methicillin sodium salt
132-92-3
White
>110°C (230°F)
C17H19N2NaO6S
640°C
Sodium (2,6-dimethoxyphenyl)penicillin; Sodium methicillin
MGFZNWDWOKASQZ-UMLIZJHQSA-M
sodium (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
23667627
402.4
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Safety and Handling

Safety and Handling

GHS H Statement
H334-H335-H315-H319-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
May cause an allergic skin reaction.

P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c

H315-H317-H319-H334-H335

EINECSNumber : 205-083-9

RTECSNumber : XH8950000

TSCA : No

storageNote1 : -30° to -10°C

Recommended Storage : Store at -20°C

SDS
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