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Methylene Blue trihydrate, Thermo Scientific Chemicals

Sensitive stain for RNA and ribonuclease

Supplier:  Thermo Scientific Chemicals J6082314

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Catalog No. AAJ6082314


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Description

Description

Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

Solubility
Soluble in water, alcohol and chloroform. Insoluble in ether.

Notes
Incompatible with strong oxidizing agents.
Specifications

Specifications

Methylene Blue trihydrate
C16H24ClN3O3S
3599847
C.I. 52015; Basic Blue 9
XQAXGZLFSSPBMK-UHFFFAOYSA-M
[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
104827
Odorless
25 g
7220-79-3
MFCD00150008
14,6060
Soluble in water,alcohol and chloroform; Insoluble in ether.
O.O.O.[Cl-].CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C
373.90
373.90 (319.86 Anhydrous)
Green
Crystalline Powder

Chemical Identifiers

7220-79-3
373.90
XQAXGZLFSSPBMK-UHFFFAOYSA-M
104827
O.O.O.[Cl-].CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C
C16H24ClN3O3S
MFCD00150008
C.I. 52015; Basic Blue 9
[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
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Safety and Handling

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

P264b-P270-P301+P312-P330-P501c

H302

EINECSNumber : 200-515-2

RTECSNumber : SP5740000

TSCA : Yes

Recommended Storage : Ambient temperatures

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RUO – Research Use Only