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Mupirocin, 92%, Thermo Scientific Chemicals

Supplier:  Thermo Scientific Chemicals J66347MF

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Catalog No. AAJ66347MF


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Description

Description

Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.

Solubility
Soluble in DMSO or methanol. Sparingly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Typical working concentrations are in the range of 0.25µg/mL-0.39µg/mL.
Specifications

Specifications

Mupirocin
Powder
77°C to 78°C
50 mg
C26H44O9
672°C
Soluble in DMSO or methanol; Sparingly soluble in water
CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)O)C)C(C)O
500.629
CHEBI:7025
92%
Mupirocin
12650-69-0
White
>110°C (230°F)
MFCD01711620
14,6302
MINDHVHHQZYEEK-HBBNESRFSA-N
9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
446596
500.62

Chemical Identifiers

12650-69-0
500.629
MINDHVHHQZYEEK-HBBNESRFSA-N
CHEBI:7025
CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)O)C)C(C)O
C26H44O9
MFCD01711620
446596
9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
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Safety and Handling

Safety and Handling

RTECSNumber : RA6907000

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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Documents

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RUO – Research Use Only