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N-Ethylmaleimide, 98+%, Thermo Scientific Chemicals
$188.32 - $565.19
Chemical Identifiers
| CAS | 128-53-0 |
|---|---|
| Molecular Formula | C6H7NO2 |
| Molecular Weight (g/mol) | 125.127 |
| MDL Number | MFCD00005509 |
| InChI Key | HDFGOPSGAURCEO-UHFFFAOYSA-N |
| Synonym | n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide |
| PubChem CID | 4362 |
| ChEBI | CHEBI:44485 |
| IUPAC Name | 1-ethylpyrrole-2,5-dione |
| SMILES | CCN1C(=O)C=CC1=O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAL0035509
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Thermo Scientific Chemicals
L0035509 |
10 g |
Each for $188.32
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AAL0035518
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Thermo Scientific Chemicals
L0035518 |
50 g |
Each for $565.19
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Description
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsCysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.
Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.
Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.
Chemical Identifiers
| 128-53-0 | |
| 125.127 | |
| HDFGOPSGAURCEO-UHFFFAOYSA-N | |
| 4362 | |
| 1-ethylpyrrole-2,5-dione |
| C6H7NO2 | |
| MFCD00005509 | |
| n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide | |
| CHEBI:44485 | |
| CCN1C(=O)C=CC1=O |
Specifications
| 128-53-0 | |
| 209°C to 211°C | |
| Pungent | |
| MFCD00005509 | |
| UN2928 | |
| Light sensitive | |
| n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide | |
| HDFGOPSGAURCEO-UHFFFAOYSA-N | |
| 1-ethylpyrrole-2,5-dione | |
| 4362 | |
| 125.13 | |
| N-Ethylmaleimide |
| 43°C to 46°C | |
| 73°C (163°F) | |
| C6H7NO2 | |
| 10 g | |
| 112448 | |
| 14,3822 | |
| Soluble in ethanol,water,chloroform,methanol and toluene. | |
| CCN1C(=O)C=CC1=O | |
| 125.127 | |
| CHEBI:44485 | |
| ≥98% |
Safety and Handling
GHS H Statement
H300-H311-H314-H318-H317
Fatal if swallowed.
Toxic in contact with skin.
Causes severe skin burns and eye damage.
Causes serious eye damage.
May cause an allergic skin reaction.
P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c
H300-H311-H314-H317-H335
DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, CORROSIVE, ORGANIC, N.O.S.
EINECSNumber : 204-892-4
RTECSNumber : UX9625000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only