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Naringin, Thermo Scientific Chemicals
A citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activity
Supplier: Thermo Scientific Chemicals J6316614
Description
A citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activityNaringin is used to prepare naringin dihydrochalcone, which is about 300-1800 times sweeter than sugar. It is a citrus bioflavonoid reported to inhibit cytochrome P450 monooxygenase activity. It also acts as an inhibitor of cytochrome P450 enzymes. It is employed as an antioxidant, lipid lowering and anticancer agent. In addition to this, it is used in a study to assess aldosterone production by a human adrenocortical cell line and to improve cognitive deficits of Alzheimer's disease.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsA citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activityNaringin is used to prepare naringin dihydrochalcone, which is about 300-1800 times sweeter than sugar. It is a citrus bioflavonoid reported to inhibit cytochrome P450 monooxygenase activity. It also acts as an inhibitor of cytochrome P450 enzymes. It is employed as an antioxidant, lipid lowering and anticancer agent. In addition to this, it is used in a study to assess aldosterone production by a human adrenocortical cell line and to improve cognitive deficits of Alzheimer′s disease.
Solubility
Soluble in water, alcohol, acetone and warm acetic acid.
Notes
Incompatible with strong oxidizing agents.
Specifications
| Naringin | |
| White to Yellow | |
| MFCD00148888,MFCD00149445,MFCD01461988 | |
| 102012 | |
| 4',5,7-Trihydroxyflavanone 7-rhamnoglucoside | |
| DFPMSGMNTNDNHN-ZPHOTFPESA-N | |
| 7-[(2S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one | |
| 74787988 | |
| Powder |
| 10236-47-2 | |
| C27H32O14 | |
| 25 g | |
| 14,6425 | |
| Soluble in water,alcohol,acetone and warm acetic acid. | |
| C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC2=CC(O)=C3C(=O)C[C@H](OC3=C2)C2=CC=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1O | |
| 580.54 | |
| 580.53 |
Chemical Identifiers
| 10236-47-2 | |
| 580.54 | |
| DFPMSGMNTNDNHN-ZPHOTFPESA-N | |
| 74787988 | |
| C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC2=CC(O)=C3C(=O)C[C@H](OC3=C2)C2=CC=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1O |
| C27H32O14 | |
| MFCD00148888,MFCD00149445,MFCD01461988 | |
| 4',5,7-Trihydroxyflavanone 7-rhamnoglucoside | |
| 7-[(2S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Warning
EINECSNumber : 233-566-4
RTECSNumber : QN6340000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only