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Phenyl chlorothionoformate, 98+%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals L0083803
Description
Phenyl chlorothionoformate has been used in stereo directed synthesis of optically active, (-)-mintlactone, synthesis of peptide α-thioesters having a variety of C-terminal amino acids, synthesis of scyllo-inositol derivatives, thionocarbonylation of unprotected thymine nucleosides, preparation of phenoxythiocarbonyl esters of protected ribonucleosides. It is also used as a reagent in the thionocarbonylation of unprotected thymine nucleosides. It forms phenoxythiocarbonyl esters of protected ribonucleosides which can be reduced by tributyltin hydride to deoxyribonucleosides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsPhenyl chlorothionoformate has been used in stereo directed synthesis of optically active, (-)-mintlactone, synthesis of peptide α-thioesters having a variety of C-terminal amino acids, synthesis of scyllo-inositol derivatives, thionocarbonylation of unprotected thymine nucleosides, preparation of phenoxythiocarbonyl esters of protected ribonucleosides. It is also used as a reagent in the thionocarbonylation of unprotected thymine nucleosides. It forms phenoxythiocarbonyl esters of protected ribonucleosides which can be reduced by tributyltin hydride to deoxyribonucleosides.
Solubility
Soluble in water.
Notes
Moisture, Heat Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
Specifications
Phenyl chlorothionoformate | |
1.248 | |
81°C (177°F) | |
C7H5ClOS | |
MFCD00004920 | |
UN3265 | |
Moisture sensitive | |
Soluble in water. | |
ClC(=S)OC1=CC=CC=C1 | |
172.63 | |
172.63 |
1005-56-7 | |
81°C to 83°C (6 mmHg) | |
Acrid | |
1.5804 | |
1 g | |
774830 | |
o-phenyl carbonochloridothioate, phenyl chlorothionoformate, o-phenyl chlorothioformate, phenyl chlorothioformate, phenyl thioxochloroformate, phenyl chlorothionocarbonate, phenoxythiocarbonyl chloride, chlorothioformic acid phenyl ester, o-phenyl chlorothionoformate, o-phenyl chlorothiocarbonate | |
KOSYAAIZOGNATQ-UHFFFAOYSA-N | |
phenyl chloromethanethioate | |
70498 | |
≥98% |
Chemical Identifiers
1005-56-7 | |
172.63 | |
KOSYAAIZOGNATQ-UHFFFAOYSA-N | |
70498 |
C7H5ClOS | |
MFCD00004920 | |
o-phenyl carbonochloridothioate, phenyl chlorothionoformate, o-phenyl chlorothioformate, phenyl chlorothioformate, phenyl thioxochloroformate, phenyl chlorothionocarbonate, phenoxythiocarbonyl chloride, chlorothioformic acid phenyl ester, o-phenyl chlorothionoformate, o-phenyl chlorothiocarbonate | |
ClC(=S)OC1=CC=CC=C1 |
Safety and Handling
GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
P210-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
H227-H314
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber : 213-736-4
TSCA : No
Recommended Storage : Keep cold; Store under Nitrogen
RUO – Research Use Only