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Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))
Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of a stabilizing cyclohexane-containing, 15-atom spacer arm.
Supplier: Thermo Scientific™ LSG22362
Description
Thermo Scientific™ Pierce LC-SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long cyclohexane-stabilized spacer arm (16.2 Ås)
Highlights:
- Ideal for coupling enzymes to antibodies as both enzyme activity and antibody specificity can be preserved after coupling
- Cyclohexane-containing spacer stabilizes the maleimide group
- Useful for the preparation of stable maleimide-activated proteins
- Reactive groups: NHS ester and maleimide
- Reactive toward: amino and sulfhydryl groups
Specifications
| Amine-Sulfhydryl | |
| LC-SMCC | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| Maleimide, NHS Ester | |
| Solid | |
| DMF, DMSO | |
| No |
| No | |
| 447.48 | |
| 16.2 AÌ | |
| Yes | |
| Pierce™ | |
| Heterobifunctional | |
| Medium (10 to 30 AÌ) | |
| 50 mg | |
| Standard | |
| Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.