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Pyrilamine maleate, Thermo Scientific Chemicals
Selective inverse agonist for the H-1 histamine receptor
Supplier: Thermo Scientific Chemicals J6324714
Description
Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsPyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.
Solubility
Soluble in water at 100mg/ml
Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Specifications
| Pyrilamine maleate | |
| White | |
| MFCD00069333 | |
| 14,7984 | |
| Soluble in water at 100mg/ml | |
| OC(=O)\C=C/C(O)=O.COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1 | |
| 401.46 | |
| 401.46 |
| 59-33-6 | |
| C21H27N3O5 | |
| 25 g | |
| pyrilamine maleate, mepyramine maleate, anisopyradamine, histosol, minihist, diaminide maleate, paraminyl maleate, antihist, histatex, histine | |
| JXYWFNAQESKDNC-BTJKTKAUSA-N | |
| (2Z)-but-2-enedioic acid; N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine | |
| 5284451 | |
| Powder |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Warning
EINECSNumber : 200-422-7
RTECSNumber : UT1225000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only