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Quinine hemisulfate monohydrate, 98+%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A1703630
Description
Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsQuinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Solubility
Soluble in a mixture of chloroform and absolute alcohol (2:1).
Notes
Light sensitive. Incompatible with strong oxidizing agents, alkalis, ammonia, strong bases and iodine.
Specifications
| Quinine hemisulfate monohydrate | |
| 217°C to 218°C (decomposition) | |
| C40H54N4O10S | |
| 250 g | |
| Light sensitive | |
| Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate | |
| ZHNFLHYOFXQIOW-OIGVVMIYNA-N | |
| O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C | |
| 782.95 | |
| 391.47 (373.46 Anhydrous) |
| 6119-70-6 | |
| Odorless | |
| MFCD00150790 | |
| 6113937 | |
| 14,8061 | |
| Soluble in a mixture of chloroform and absolute alcohol (2:1). | |
| −241° (c=2 in 0.1M HCl) | |
| (R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate | |
| 134129495 | |
| 99% |
Chemical Identifiers
| 6119-70-6 | |
| 782.95 | |
| ZHNFLHYOFXQIOW-OIGVVMIYNA-N | |
| 134129495 | |
| O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C |
| C40H54N4O10S | |
| MFCD00150790 | |
| Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate | |
| (R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate |
Safety and Handling
GHS H Statement
H301-H334-H317
Toxic if swallowed.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.
P261-P264b-P270-P271-P272-P280-P285-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P333+P313-P362-P501c
H302+H312+H332-H315-H317-H319-H334-H335
EINECSNumber : 212-359-2
RTECSNumber : VA8440000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only