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Retinol, 95%, synthetic, Thermo Scientific Chemicals

All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells.

Supplier:  Thermo Scientific Chemicals J6207903

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Catalog No. AAJ6207903


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Description

Description

It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient
• All-trans-retinol is involved in hormonal signaling via the retinoid receptors
• It is an important regulator of cell division and apoptosis
• Deficiency can lead to vision, bone, immune, and skin disorders

Applications
• Suitable for research on cell differentiation, embryonic development, immunology and more
• Laboratory grade quality, for research use only

Specifications

Specifications

Retinol
68-26-8
C20H30O
1 g
Light and moisture sensitive
retinol, vitamin a, all-trans-retinol, vitamin a1, alphalin, axerophthol, vitamin a alcohol, oleovitamin a, chocola a, alphasterol
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
445354
286.46
Crystalline Solid
synthetic
White to Yellow
MFCD00001552
403040
14,10013
Practically insoluble in water or glycerol; soluble in absolute alcohol, methanol, chloroform,ether,fats and oils.
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C
286.459
CHEBI:17336
95%

Chemical Identifiers

68-26-8
MFCD00001552
445354
C20H30O
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
CHEBI:17336
Safety and Handling

Safety and Handling

GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.

P201-P202-P264b-P270-P280-P280i-P301+P312-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c

H302-H315-H319-H361d-H500

EINECSNumber : 200-683-7

RTECSNumber : VH6750000

TSCA : Yes

Recommended Storage : Store at -20°C; Store under Nitrogen

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RUO – Research Use Only