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Retinol, 95%, synthetic, Thermo Scientific Chemicals
All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells.
Supplier: Thermo Scientific Chemicals J62079MD
Description
It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient
• All-trans-retinol is involved in hormonal signaling via the retinoid receptors
• It is an important regulator of cell division and apoptosis
• Deficiency can lead to vision, bone, immune, and skin disorders
Applications
• Suitable for research on cell differentiation, embryonic development, immunology and more
• Laboratory grade quality, for research use only
Specifications
| Retinol | |
| 68-26-8 | |
| C20H30O | |
| 250 mg | |
| Light and moisture sensitive | |
| retinol, vitamin a | |
| FPIPGXGPPPQFEQ-OVSJKPMPSA-N | |
| (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol | |
| 445354 | |
| 286.46 | |
| Crystalline Solid |
| synthetic | |
| White to Yellow | |
| MFCD00001552 | |
| 403040 | |
| 14,10013 | |
| Practically insoluble aq. soln. or glycerol; soluble in absolute alcohol, methanol, chloroform,ether,fats and oils. | |
| C\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C | |
| 286.46 | |
| CHEBI:17336 | |
| 95% |
Chemical Identifiers
| 68-26-8 | |
| MFCD00001552 | |
| 445354 |
| C20H30O | |
| FPIPGXGPPPQFEQ-OVSJKPMPSA-N | |
| CHEBI:17336 |
Safety and Handling
GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
P201-P202-P264b-P270-P280-P280i-P301+P312-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
H302-H315-H319-H361d-H500
EINECSNumber : 200-683-7
RTECSNumber : VH6750000
TSCA : Yes
Recommended Storage : Store at -20°C; Store under Nitrogen
RUO – Research Use Only