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Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format

Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.

Supplier:  Thermo Scientific™ 24510

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Catalog No. PI24510


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Description

Description

Thermo Scientific™ Pierce Sulfo-NHS is pure N-hydroxysulfosuccinimide, the essential compound needed to prepare water-soluble, amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.

Highlights:

  • Forms an acyl amino ester with carboxyl groups when used with the EDC
  • Sulfo-NHS-activated molecule reacts efficiently with primary amines, resulting in stable amide bond
  • Allows for two-step EDC reactions between carboxyl- and amine-containing molecules
  • Sulfo-NHS-activated molecule can be stabilized by drying, allowing manufacture of amine-reactive probes and surfaces
  • Reactive groups: Sulfo-NHS
  • Reactive toward: amino groups (upon activation of carboxylates)
Specifications

Specifications

Amine-Carboxyl
Sulfo-NHS
No
No
Pierce™
Heterobifunctional
Short (<10 Å)
500 mg
Standard, Single-use, Premium-grade
Crosslinker
No
217.13
Upon receipt store at 4°C.
Ambient
Chemical Labeling
Carbodiimide
Powder
Water
Yes
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For Research Use Only. Not for use in diagnostic procedures.