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tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals
$59.36 - $540.55
Chemical Identifiers
| CAS | 18162-48-6 |
|---|---|
| Molecular Formula | C6H15ClSi |
| Molecular Weight (g/mol) | 150.721 |
| MDL Number | MFCD00000501 |
| InChI Key | BCNZYOJHNLTNEZ-UHFFFAOYSA-N |
| Synonym | tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride |
| PubChem CID | 28928 |
| ChEBI | CHEBI:85071 |
| IUPAC Name | tert-butyl-chloro-dimethylsilane |
| SMILES | CC(C)(C)[Si](C)(C)Cl |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAA1306406
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Thermo Scientific Chemicals
A1306406 |
5 g |
Each for $59.36
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AAA1306414
|
Thermo Scientific Chemicals
A1306414 |
25 g |
Each for $197.23
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AAA1306422
|
Thermo Scientific Chemicals
A1306422 |
100 g |
Each for $540.55
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Description
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applicationstert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.
Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
Chemical Identifiers
| 18162-48-6 | |
| 150.721 | |
| BCNZYOJHNLTNEZ-UHFFFAOYSA-N | |
| 28928 | |
| tert-butyl-chloro-dimethylsilane |
| C6H15ClSi | |
| MFCD00000501 | |
| tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride | |
| CHEBI:85071 | |
| CC(C)(C)[Si](C)(C)Cl |
Specifications
| 124°C to 126°C | |
| 18162-48-6 | |
| C6H15ClSi | |
| MFCD00000501 | |
| 505999 | |
| tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride | |
| BCNZYOJHNLTNEZ-UHFFFAOYSA-N | |
| tert-butyl-chloro-dimethylsilane | |
| 28928 | |
| 150.73 | |
| Pungent | |
| 0.81 |
| 86°C to 89°C | |
| 5 g | |
| (CH3)3CSi(CH3)2Cl | |
| UN2925 | |
| 22°C (72°F) | |
| Soluble in chloroform and ethyl acetate. Insoluble in water. | |
| CC(C)(C)[Si](C)(C)Cl | |
| 150.721 | |
| CHEBI:85071 | |
| 97% | |
| Moisture sensitive | |
| tert-Butyldimethylchlorosilane |
Safety and Handling
GHS H Statement
H228-H314-H318
Flammable solid.
Causes severe skin burns and eye damage.
Causes serious eye damage.
P210-P240-P241-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
H228-H314-H335
DOTInformation : Hazard Class: 8; Packaging Group: I
EINECSNumber : 242-042-4
RTECSNumber : VV2000000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only