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Thiamphenicol, Thermo Scientific Chemicals

The methyl-sulfonyl analogue of chloramphenicol

Supplier:  Thermo Scientific Chemicals J6357514

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Catalog No. AAJ6357514


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Description

Description

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications

Specifications

Thiamphenicol
White to Yellow
MFCD00467983
2819542
thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
OTVAEFIXJLOWRX-NXEZZACHSA-N
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
27200
356.22
15318-45-3
C12H15Cl2NO5S
25 g
14,9301
Soluble in acetonitrile or DMF; Slightly soluble in water
CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O
356.214
CHEBI:32215
Powder

Chemical Identifiers

15318-45-3
356.214
OTVAEFIXJLOWRX-NXEZZACHSA-N
27200
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
C12H15Cl2NO5S
MFCD00467983
thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
CHEBI:32215
CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O
Safety and Handling

Safety and Handling

EINECSNumber : 239-355-3

RTECSNumber : AB6680000

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only