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Tolbutamide, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals B2169809
Description
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
Solubility
Soluble in chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Specifications
| Tolbutamide | |
| 128°C to 130°C | |
| MFCD00027169 | |
| 1984428 | |
| tolbutamide, orinase, 1-butyl-3-tosylurea, tolbutamid, aglicid, arkozal, artosin, diabetol, dolipol, rastinon | |
| JLRGJRBPOGGCBT-UHFFFAOYSA-N | |
| 1-butyl-3-(4-methylphenyl)sulfonylurea | |
| 5505 | |
| 270.35 |
| 64-77-7 | |
| C12H18N2O3S | |
| 10 g | |
| 14,9507 | |
| Soluble in chloroform. | |
| CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C | |
| 270.347 | |
| CHEBI:27999 | |
| 98% |
Chemical Identifiers
| 64-77-7 | |
| 270.347 | |
| JLRGJRBPOGGCBT-UHFFFAOYSA-N | |
| 5505 | |
| 1-butyl-3-(4-methylphenyl)sulfonylurea |
| C12H18N2O3S | |
| MFCD00027169 | |
| tolbutamide, orinase, 1-butyl-3-tosylurea, tolbutamid, aglicid, arkozal, artosin, diabetol, dolipol, rastinon | |
| CHEBI:27999 | |
| CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C |
Safety and Handling
GHS H Statement
H302-H317
Harmful if swallowed.
May cause an allergic skin reaction.
P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c
H302-H317
EINECSNumber : 200-594-3
RTECSNumber : YS4550000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only