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Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals

Supplier:  Thermo Scientific Chemicals A1744430

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Catalog No. AAA1744430


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Description

Description

Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

Solubility
Miscible with ethanol, ether and benzene. Immiscible with water.

Notes
Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.comStore in a cool place. Light and heat sensitive. Incompatible with strong oxidizing agents and bases.
Specifications

Specifications

Trichloromethyl chloroformate
-57°C
128°C
98%
C2Cl4O2
ClCO2CCl3
250 g
970225
14,3334
Miscible with ethanol,ether and benzene. Immiscible with water.
ClC(=O)OC(Cl)(Cl)Cl
197.82
197.83
503-38-8
1.64
>110°C (230°F)
Pungent
1.457
MFCD00015553
UN3390
Moisture sensitive
diphosgene, trichloromethyl chloroformate, diphosgen, difosgen czech, perchloromethyl formate, unii-po4q4r80lv, hsdb 371, carbonochloridic acid, trichloromethyl ester, methanol, trichloro-, chloroformate, chloroformic acid trichloromethyl ester
HCUYBXPSSCRKRF-UHFFFAOYSA-N
trichloromethyl carbonochloridate
10426
98%

Chemical Identifiers

503-38-8
197.82
HCUYBXPSSCRKRF-UHFFFAOYSA-N
10426
ClC(=O)OC(Cl)(Cl)Cl
C2Cl4O2
MFCD00015553
diphosgene, trichloromethyl chloroformate, diphosgen, difosgen czech, perchloromethyl formate, unii-po4q4r80lv, hsdb 371, carbonochloridic acid, trichloromethyl ester, methanol, trichloro-, chloroformate, chloroformic acid trichloromethyl ester
trichloromethyl carbonochloridate
Safety and Handling

Safety and Handling

GHS H Statement
H330-H314-H318
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P262-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

H300+H330-H314

DOTInformation : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, CORROSIVE, N.O.S.

EINECSNumber : 207-965-9

RTECSNumber : LQ7350000

TSCA : Yes

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only