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Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A1744430
Description
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.
Solubility
Miscible with ethanol, ether and benzene. Immiscible with water.
Notes
Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.comStore in a cool place. Light and heat sensitive. Incompatible with strong oxidizing agents and bases.
Specifications
Trichloromethyl chloroformate | |
-57°C | |
128°C | |
98% | |
C2Cl4O2 | |
ClCO2CCl3 | |
250 g | |
970225 | |
14,3334 | |
Miscible with ethanol,ether and benzene. Immiscible with water. | |
ClC(=O)OC(Cl)(Cl)Cl | |
197.82 | |
197.83 |
503-38-8 | |
1.64 | |
>110°C (230°F) | |
Pungent | |
1.457 | |
MFCD00015553 | |
UN3390 | |
Moisture sensitive | |
diphosgene, trichloromethyl chloroformate, diphosgen, difosgen czech, perchloromethyl formate, unii-po4q4r80lv, hsdb 371, carbonochloridic acid, trichloromethyl ester, methanol, trichloro-, chloroformate, chloroformic acid trichloromethyl ester | |
HCUYBXPSSCRKRF-UHFFFAOYSA-N | |
trichloromethyl carbonochloridate | |
10426 | |
98% |
Chemical Identifiers
503-38-8 | |
197.82 | |
HCUYBXPSSCRKRF-UHFFFAOYSA-N | |
10426 | |
ClC(=O)OC(Cl)(Cl)Cl |
C2Cl4O2 | |
MFCD00015553 | |
diphosgene, trichloromethyl chloroformate, diphosgen, difosgen czech, perchloromethyl formate, unii-po4q4r80lv, hsdb 371, carbonochloridic acid, trichloromethyl ester, methanol, trichloro-, chloroformate, chloroformic acid trichloromethyl ester | |
trichloromethyl carbonochloridate |
Safety and Handling
GHS H Statement
H330-H314-H318
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
P260-P262-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
H300+H330-H314
DOTInformation : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, CORROSIVE, N.O.S.
EINECSNumber : 207-965-9
RTECSNumber : LQ7350000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only