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Tunicamycin, 95%, Thermo Scientific Chemicals

 

Supplier:  Thermo Scientific Chemicals J62217MA

Catalog No. AAJ62217MA


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Description

Description

Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during dolichol-linked glycoprotein synthesis. Dose-dependent inhibition of DNA synthesis may be related to the alteration of glycoproteins, which thereby affects the transport of thymidine into cells. Additionally, tunicamycin has been reported to prevent cell cycle progression in primary cultures of rat glial cells, as well as inhibit lipid-mediated protein glycosylation in chick or mouse fibroblasts in a dose-dependent manner.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during d
Specifications

Specifications

Tunicamycin
Powder
C39H64N4O16
UN3462
14,9819
844.95
White to Yellow
Light and moisture sensitive
Tunicamycin
11089-65-9
MFCD00065709
6888090
Soluble in methanol, ethanol, DMSO, or DMF
95%
10 mg

Chemical Identifiers

11089-65-9
C39H64N4O16
MFCD00065709
Safety and Handling

Safety and Handling

GHS H Statement
H300-H330-H373
Fatal if swallowed.
Fatal if inhaled.
May cause damage to organs through prolonged or repeated exposure.

P260-P264b-P270-P271-P284-P301+P310-P304+P340-P310-P314-P330-P501c

H300+H330-H373

DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.

RTECSNumber : YO7980200

TSCA : No

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only