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Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns
Designed for method optimization and parameter screening for capture of monoclonal antibodies. Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns come ready-to-use for convenience.
Supplier: Cytiva 17547415
Description
- Ready-to-use columns for convenient process development
- Rigid, highly cross-linked agarose matrix
- Bed height of 10cm is designed to allow method optimization and parameter screening
- Easily connected in series to achieve 20cm bed height
- Small bed volume (4.7mL) gives fast result and minimal sample/buffer consumption
- Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity
MabSelect
- For capture of MAbs from large sample volumes
- Prepacked with protein A-derived media
- Compatible with high flow rates and high pressure when scaling up
- Increased binding capacity enables purification of MAbs from high-level expression feedstock
- Also optimized for Fc-fusion proteins
- Very low, unspecific binding due to high ligand selectivity and matrix hydrophilicity
- Prepacked with protein A-derived media
- With novel, alkali-tolerant recombinant protein A ligand that provides greater stability and allows use of 0.1 to 0.5M sodium hydroxide for cleaning-in-place (CIP)
- Enhanced protease resistance resulting in lower ligand leakage
- High dynamic binding capacity
Specifications
| 8M Urea, 6M Guanidine Hydrochloride, 2% Benzyl Alcohol or 20% Ethanol | |
| Stoppers at the inlet and outlet | |
| Filter | |
| ≈60mg Human IgG | |
| HiScreen MabSelect SuRe LX Prepacked Column | |
| 10cm | |
| Alkali-stabilized Protein A-derived (E. coli) | |
| Polypropylene | |
| 3bar | |
| 2° to 8°C |
| HiScreen MabSelect SuRe LX Prepacked Column | |
| 1 x 4.7mL | |
| 0.3 in. | |
| 0.77cm | |
| 3.93 in. | |
| Designed for method optimization and parameter screening for capture of monoclonal antibodies | |
| Epoxy Activation | |
| 85μm | |
| 3 to 12 | |
| Column |