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Hydroxychloroquine sulfate, 98%, Thermo Scientific Chemicals
Hydroxychloroquine sulfate, CAS # 747-36-4, is a chemical compound with antiparasitic, antiviral, and anti-rheumatic activities.
Supplier: Thermo Scientific Chemicals 263010250
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Hydroxychloroquine sulfate shows antimalarial activity against malaria parasites mainly in the intra-erythrocytic phase of its life cycle. It acts by inhibiting the heme polymerase inside the food vacuole of the parasites
- It shows an inhibitory activity in autophagy preventing the lysosome fusion with the autophagosome
- Some studies demonstrated that hydroxychloroquine sulfate, due to its antiviral activity can restrict HIV infection in vitro
Applications
- Hydroxychloroquine sulfate displays antiviral and anti-rheumatic activities
- In vitro and in vivo experiments have been performed to investigate the role of hydroxychloroquine sulfate in the treatment of SARS-CoV-2 disease
- Hydroxychloroquine sulfate can be used in immunofluorescence assays to evaluate the antiviral mechanisms in dengue virus-2 infection. In this disease, this compound can activate the innate immune response
Specifications
| Hydroxychloroquine sulfate | |
| 240.0°C | |
| 2% max. (105°C, 2 hrs.) | |
| 0.98 | |
| C18H26ClN3O·H2SO4 | |
| 25 g | |
| hydroxychloroquine sulfate, hydroxychloroquine sulphate, ercoquin, plaquinol, toremonil, 2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate, hydroxychloroquine sulfate usp, plaquenil tn, hydroxychloroquine; sulfuric acid, dsstox_cid_27788 | |
| JCBIVZZPXRZKTI-UHFFFAOYSA-N | |
| 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid | |
| 12947 | |
| 98% |
| 747-36-4 | |
| White | |
| Authentic | |
| Glass bottle | |
| MFCD00078203 | |
| 15, 4857 | |
| Solubility in water: soluble. Other solubilities: practically insoluble in alcohol,chloroform,,ether,acetone and acetic acid | |
| CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O | |
| 433.96 | |
| 433.96 | |
| Crystalline Powder |
Chemical Identifiers
| 747-36-4 | |
| 433.96 | |
| JCBIVZZPXRZKTI-UHFFFAOYSA-N | |
| 12947 | |
| CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O |
| C18H26ClN3O·H2SO4 | |
| MFCD00078203 | |
| hydroxychloroquine sulfate, hydroxychloroquine sulphate, ercoquin, plaquinol, toremonil, 2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate, hydroxychloroquine sulfate usp, plaquenil tn, hydroxychloroquine; sulfuric acid, dsstox_cid_27788 | |
| 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid |
Safety and Handling
Causes serious eye irritation, Harmful if swallowed
Serious eye damage/eye irritation (category 2), Acute toxicity (category 4)
EINECSNumber : 212-019-3
RUO – Research Use Only